Application: We recommend the following antibodies for sandwich immunoassay (Capture - Detection): DMAB-CPT761 - DMAB-CPT762
Summary
Specifications
Antibody Isotype
IgG
Clone
341585G2
Species Reactivity
Human
Immunogen
TJP2 fusion protein
Conjugate
Unconjugated
Applications
Application Notes
We recommend the following antibodies for sandwich immunoassay (Capture - Detection): DMAB-CPT761 - DMAB-CPT762 Cytometric Bead Array: 0.625-20 ng/mL
General Notes
This product (Catalog No. DMAB-CPT761) is a rabbit-derived monoclonal antibody raised against human TJP2. It has been affinity purified by Protein A. Tight junction protein 2 (TJP2), or ZO-2, is a protein-coding gene (607709 - OMIM) that acts as a scaffold at tight junctions in epithelial and endothelial cells, linking transmembrane proteins like claudins to the actin cytoskeleton. Mutations in TJP2 cause severe, early-onset progressive familial intrahepatic cholestasis type 4 (PFIC4) and, rarely, adult-onset deafness. It is crucial for maintaining intercellular barrier function in the liver and other organs. DMAB-CPT761 is suitable for use in Cytometric Bead Array (0.625-20 ng/mL) application. DMAB-CPT761 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
Tight junction protein 2; Tight junction protein ZO 2; TJP2; X104; ZO 2; ZO2; Zona occludens protein 2; Zonula occludens protein 2
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