SARS-CoV-2 Nucleocapsid IgG ELISA Kit (DEIASL060)

Regulatory status: For research use only, not for use in diagnostic procedures.

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Size
96T
Sample
Serum, plasma, saliva and nasal fluid
Species Reactivity
Human
Intended Use
This immunoassay kit is intended for the qualitative determination of anti-SARS-CoV-2(N)-IgG in human serum, plasma, saliva and nasal fluid.
Storage
2-8°C for 6 months.

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References


Self-Collected Anterior Nasal and Saliva Specimens versus Health Care Worker-Collected Nasopharyngeal Swabs for the Molecular Detection of SARS-CoV-2

JOURNAL OF CLINICAL MICROBIOLOGY

Authors: Hanson, K. E.; Barker, A. P.; Hillyard, D. R.; Gilmore, N.; Barrett, J. W.; Orlandi, R. R.; Shakir, S. M.

We prospectively compared health care worker-collected nasopharyngeal swabs (NPS) to self-collected anterior nasal swabs (ANS) and straight saliva for the diagnosis of coronavirus disease 2019 (COVID-19) in 354 patients. The percent positive agreement between NPS and ANS or saliva was 86.3% (95% confidence interval [CI], 76.7 to 92.9%) and 93.8% (95% CI, 86.0 to 97.9%), respectively. The percent negative agreement was 99.6% (95% CI, 98.0 to 100.0%) for NPS versus ANS and 97.8% (95% CI, 95.3 to 99.2%) for NPS versus saliva. More cases were detected by the use of NPS (n = 80) and saliva (n = 81) than by the use of ANS (n = 70), but no single specimen type detected all severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

The immune roadmap for understanding multi-system inflammatory syndrome in children: opportunities and challenges

NATURE MEDICINE

Authors: Martinez, Olivia M.; Bridges, Nancy D.; Goldmuntz, Ellen; Pascual, Virginia

In the spring of 2020, a series of reports from Europe and the USA described clusters of children and adolescents presenting with a life-threatening, hyperinflammatory syndrome - called 'multi-system inflammatory syndrome in children' (MIS-C) - that was seemingly linked to prior exposure to the coronavirus SARS-CoV-2. In June 2020, the US National Institutes of Health convened a workshop of immunologists and clinicians to discuss emerging knowledge and identify key questions surrounding MIS-C, with a focus on innate and adaptive immunity, genetics and epigenetics. This Meeting Report describes the main findings from the workshop.

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