Specifications
Species Reactivity
Human, Mouse
Immunogen
A peptide corresponding to amino acids 384–408 of the human MLH1 protein
Applications
General Notes
282B exhibits high specificity, sensitivity, and strong binding affinity for human MLH1 protein in cells and tissues. It reliably detects and localizes the target protein in immunodetection assays, including immunoblotting and immunohistochemistry. In addition to human MLH1, this antibody cross-reacts with the homologous mouse MLH1 protein, supporting its application in both human and mouse studies.
Target
Alternative Names
MutL homolog 1; MLH 1; MLH1; COCA2
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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Kwasniewska, A; Postawski, K; et al. Immunohistochemical detection of hMLH1 and hMSH2 proteins in vulvar carcinoma. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 15:955-961(2005).
Offer, SM; Pan-Hammarstrom, Q; et al. Unique DNA Repair Gene Variations and Potential Associations with the Primary Antibody Deficiency Syndromes IgAD and CVID. PLOS ONE 5:-(2010).
COA
Certificate of Analysis
