Magic™ Rabbit Anti-Human MDC1 Monoclonal antibody, clone 351570E6

Antibody Isotype

IgG

Clone

351570E6

Species Reactivity

Human

Immunogen

MDC1 fusion protein

Conjugate

Application Notes

We recommend the following antibodies for sandwich immunoassay (Capture - Detection):
DMAB-CPT1185 - DMAB-CPT1186

General Notes

This product (Catalog No. DMAB-CPT1186) is a rabbit-derived monoclonal antibody raised against human MDC1. It has been affinity purified by Protein A. MDC1, also named as KIAA0170 or NFBD1, is a 2089 amino acid protein, which contains two BRCT domains and one FHA domain. MDC1 localizes in the nucleus and is highly expressed in testis. MDC1 is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. MDC1 may serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked.
DMAB-CPT1186 is suitable for use in CBA(Det), ELISA(Det) applications.
DMAB-CPT1186 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

NFBD1; NFBD 1; MDC 1; 240469G11; mediator of DNA damage checkpoint 1; MDC1; KIAA0170

Entrez Gene ID

UniProt ID