Magic™ Rabbit Anti-Human LYPD3 Monoclonal antibody, clone 351458G5

Antibody Isotype

IgG

Clone

351458G5

Species Reactivity

Human

Immunogen

LYPD3 fusion protein

Conjugate

Application Notes

We recommend the following antibodies for sandwich immunoassay (Capture - Detection):
DMAB-CPT1007 - DMAB-CPT1008
Cytometric Bead Array: 0.156-20 ng/mL

General Notes

This product (Catalog No. DMAB-CPT1008) is a rabbit-derived monoclonal antibody raised against human LYPD3. It has been affinity purified by Protein A. Ly6 / PLAUR domain-containing protein 3, also known as GPI-anchored metastasis-associated protein C4.4A homolog, Matrigel-induced gene C4 protein, MIG-C4, and LYPD3, is a cell membrane protein that contains two UPAR/Ly6 domains. Human LYPD3 contains two UPAR/Ly6 domains. LYPD3 is expressed in the placenta, skin, and urothelium. It is found in suprabasal keratinocytes of chronic wounds. Weak expression of LYPD3 is found in the esophagus and peripheral blood mononuclear cells. It is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression of LYPD3 is found in the tumor component of some noninvasive superficial lesions and invasive and metastatic urothelial cancers. LYPD3 is upregulated in migrating keratinocytes during epithelisation of incisional skin wounds. LYPD3 supports cell migration. It may be involved in urothelial cell-matrix interactions. It may also be involved in tumor progression.
DMAB-CPT1008 is suitable for use in Cytometric Bead Array (0.156-20 ng/mL) application.
DMAB-CPT1008 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

Ly6/PLAUR domain-containing protein 3; C4.4A; LYPD3; MIG-C4

Entrez Gene ID

UniProt ID