Magic™ Rabbit Anti-Human GPC1 Monoclonal antibody, clone 351318F23

Antibody Isotype

IgG

Clone

351318F23

Species Reactivity

Human

Immunogen

Fusion Protein

Conjugate

Application Notes

We recommend the following antibodies for sandwich immunoassay (Capture - Detection):
DMAB-CPT927 - DMAB-CPT928

General Notes

This product (Catalog No. DMAB-CPT927) is a rabbit-derived monoclonal antibody raised against human GPC1. It has been affinity purified by Protein A. Glypicans are a family of HSPGs that are attached to the cell membrane by a glycosyl-phosphatidylinositol anchor. Glypicans are considered to have the ability to modulate the activities of HBGFs. The expression of glypicans is regulated temporally and spatially during development, suggesting they are involved in development and morphogenesis. To date, six glypicans (GPC1 to GPC6) have been identified in mammals. GPC1 is most ubiquitously expressed in adult tissues. GPC1 promotes efficient signaling by HBGFs and plays a critical role in cell growth and differentiation. GPC1 is involved in tumorigenesis and angiogenesis, and is frequently overexpressed in several types of tumors including pancreatic carcinoma, breast cancer and glioma.
DMAB-CPT927 is suitable for use in CBA(Cap), ELISA(Cap) applications.
DMAB-CPT927 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

glypican 1; Glypican-1; glypican1; glypican; FLJ38078

Entrez Gene ID

UniProt ID