Contents of Kit
1. Polystyrene microwell ELISA plates coated with a purified antigen(12-1 x 8 wells), with holder in foil package containing desiccants
2. Negative Control, 1 vial of buffer 1.2 mL
3. Positive Control, 1 vial of buffer 1.2 mL
4. Calibrator A, 1 vial of buffer containing preservative, prediluted, 1.2 mL
5. Calibrator B, 1 vial of buffer containing preservative, prediluted, 1.2 mL
6. Calibrator C, 1 vial of buffer containing preservative, prediluted, 1.2 mL
7. Calibrator D, 1 vial of buffer containing preservative, prediluted, 1.2 mL
8. Sample Diluent, 1 vial – colored straw containing PBS-buffered saline, protein stabilizers and preservative, 50 mL.
9. Antibody Enzyme Conjugate, colored blue containing buffer, protein stabilizers and preservative, 12 mL
10. Wash Buffer (20 ×), 50 mL
11. TMB Chromogen, containing stabilizers, 10 mL
12. Stop Solution, Colorless, 10 mL
General Description
GAD-Ab, or Glutamic Acid Decarboxylase Autoantibodies, are antibodies that target the glutamic acid decarboxylase (GAD) enzyme, which is crucial for producing GABA, an inhibitory neurotransmitter. These antibodies are associated with several autoimmune conditions, most notably Stiff Person Syndrome (SPS) and Type 1 Diabetes (T1D). Testing for GAD-Ab can help in the prediction, diagnosis, and management of these conditions, although their correlation with disease severity or therapeutic response is not always clear. Two vertebrate genes, GAD1 and GAD2, encode distinct GAD proteins: GAD67 and GAD65. GAD1 and GAD2 sequences are highly similar to each other, and they share a common intron-exon organization, indicating a common origin.
COA
Publication 
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