Product Overview
The E. coli derived 39.7 kDa recombinant protein contains the HSV-2 gD immunodominant regiona 266-394 amino acids, fused with 26 kDa GST-tag.
Molecular Weight
~39.7 kDa
Alternative Names
Human herpes simplex virus; HSV; HSV gD; HSV Glycoprotein D; HSV2 gD; HSV-2 gD; HSV-2 US6; HSV2 US6
Purity
>92% , based on SDS PAGE
Buffer
50mM Tris-HCl (pH8.0), 150mM NaCl and 8M urea
Storage
Keep it at 4°C if used within a month. For long term storage, split it into small aliquots and keep at -80°C. Avoid repeated freezing and thawing. The product will be expired one year after receiving if stored properly. Non-hazardous. No MSDS required.
Introduction
Human herpes simplex virus (HSV), also known as human herpes virus (HHV), is a large enveloped double stranded DNA virus that belongs to the Herpesviridae family, subfamily Alphaherpesvirinae. Human HSV exists as two distinct serotypes, herpes simplex virus type -1 (HSV-1) and type -2 (HSV-2). Both HSV-1 and HSV-2 are neurotrophic viruses that invade the central nervous system (CNS), where they replicate, and have the capacity to establish a latent infection. HSV entry into the host cell requires viral glycoproteins gB, gD, gH and gL. Glycoprotein D (gD) is a structural component of the HSV envelope that has receptor binding activity and can bind specific proteins which mediate viral entry into the host cell.
Keywords
Human herpes simplex virus; HSV; HSV gD; HSV Glycoprotein D; HSV2 gD; HSV-2 gD; HSV-2 US6; HSV2 US6
Citations
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