Description
Kolliphor HS 15 is a non-ionic detergent obtained by reacting 15 moles of ethylene oxide with 1 mole of 12-hydroxy stearic acid.
Kolliphor HS 15 is a potent non-ionic solubilizer and emulsifying agent, with low toxicity. Ideal for solubilizing low-solubility actives in microemulsions, it helps tackle even the toughest solubilization challenges. It is used for manufacturing aqueous parenteral preparations with vitamins A, D, E and K, plus lipophilic APIs such as propanidid, miconazole, alfadolone, alfaxalone, nifedipine, and piroxicam. Kolliphor® HS 15 is soluble in water, ethanol, and 2- propanol. As a solubilizer, it is particularly suitable for parenteral and oral dosage forms, and lends itself well to veterinary formulations. pH 6-7.