Human High Molecular Weight & Total Adiponectin ELISA KIT (DEIA-PY021)

Regulatory status: For research use only, not for use in diagnostic procedures.

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Size
96T
Sample
serum, plasma
Intended Use
The HMW & Total Adiponectin ELISA is designed for the quantitative determination of HMW and total adiponectin in human serum and plasma (EDTA, heparin, and citrate) samples.
Storage
2-8°C
Precision
Sensitivity
LoB: 0.015 ng/mL LoD: 0.034 ng/mL.
General Description
AdiponectIn is a 244 amino acid protein and one of several known adipocytokines secreted by the adipocyte. Adiponectin circulates in the blood in various oligomeric complexes ranging from dimeric to "bouquet" structures of 9 or more proteins which include HMW adiponectin (12-mer or 18-mer). Functions of adiponectin include protection against atherosclerosis, improvement of insulin sensitivity and prevention of hepatic fibrosis. In recent years, the relationship between these physiological actions and the multimeric structure of circulating adiponectin has attracted wide attention, and data has shown that the ratio of circulating HMW adiponectin to total adiponectin is more informative than total adiponectin levels alone.

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