Recombinant rubella virus E1 protein [GST]

Nature

Recombinant

Tag/Conjugate

GST

Alternative Names

E2 protein; Rubella; Measles protein; Measles; E2 glycoprotein

Format

Liquid

Concentration

Batch dependent - please inquire should you have specific requirements

Buffer

20mM Tris-HCl pH 8.0, 1.5M urea, 10mM b-mercaptoethanol and 25% glycerol

Preservative

None

Storage

Stable at 4°C for 1 week, Freeze at -18°C for longer periods.

Introduction

Rubella virus is the only member of the Rubrivirus genus of the Togavirus family. Unlike most Togaviruses it is NOT arthropod borne, but is acquired via the respiratory route. It is an enveloped (toga=cloak), non-segmented, positive sense, RNA virus and replicates in the cytoplasm. It consists of 3 structural proteins; E1,E2 membrane bound glycoproteins, and C capsid protein. The the two envelope glycoproteins E2 and E1 are found as a heterodimeric spike complex embedded in the lipid envelope.

Antigen Description

Rubella virus is an enveloped positive-strand RNA virus of the family Togavridae: Virions are composed of three structural proteins: a capsid and two membrane-spanning glycoproteins, E2 and E1. During virus assembly, the capsid interacts with genomic RNA to form nucleocapsids. The rubella virus (RV) structural proteins: capsid, E2, and E1 are synthesized as a polyprotein precursor. The signal peptide that initiates translocation of E2 into the lumen of the endoplasmic reticulum remains attached to the carboxy terminus of the capsid protein after cleavage by signal peptidase.

Keywords

E2 protein;Rubella;Measles protein;Measles;E2 glycoprotein