Inactivated HCoV-NL63 Lysate

Product Overview

Coronavirus NL63 is a Group 1 CoV, propagated in the Vero cell line. Viral lysate is purified using sucrose density gradient ultracentrifugation, disrupted in the presence of detergent and heat inactivated.

Nature

Native

Tag/Conjugate

unconjugated

Alternative Names

HCoV NL63; HCoV; NL63

Format

Liquid

Buffer

0.5% Triton X-100 non-ionic detergent/0.6 M KCl

Preservative

None

Storage

Store at -65°C or below.

Introduction

The coronaviruses are a family of related RNA viruses within the order Nidovirales. They contain a positive-sense, single-stranded, 26-32kb RNA genome protected by a nucleocapsid of helical symmetry. Their viral capsids are surrounded by a lipid envelope, which is interrupted by trimeric Spike proteins that project from the capsid surface. Human coronavirus NL63 (HCoV-NL63) is a species of alphacoronavirus that was first identified in 2004 in a seven-month-old child in the Netherlands. HCoV-NL63 infection has since been confirmed worldwide and is associated with many common symptoms and diseases, such as moderate upper respiratory tract infections, severe lower respiratory tract infection, croup and bronchiolitis.

Keywords

HCoV NL63; HCoV; NL63