HIV type 1 Glycoprotein 120 nef Mosaic (DAG4272)

HIV type 1 Glycoprotein 120 nef Mosaic, recombinant protein from E. coli Datasheet

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Product Overview
Recombinant HIV-Ι gp120 nef Mosaic
Specificity
Immunoreactive with all sera of HIV-I infected individuals.
Nature
Recombinant
Tag/Conjugate
Unconjugated
Purity
Protein is > 95% pure as determined by 10% PAGE (coomassie staining) and RP-HPLC.
Concentration
1mg/ml, 10mM Tris-HCl, pH 4.5, 100mM Sodium Phosphate and 8M urea.
Storage
2-8°C short term, -20°C long term
Introduction
Human immunodeficiency virus (HIV) is a lentivirus (a member of the retrovirus family) that causes acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells. The four major routes of transmission are unsafe sex, contaminated needles, breast milk, and transmission from an infected mother to her baby at birth (perinatal transmission). Screening of blood products for HIV has largely eliminated transmission through blood transfusions or infected blood products in the developed world.
Antigen Description
HIV-1 Nef is one of the accessory proteins synthesized in the early stage of AIDS virus reproduction and is abundantly found in infected cells. The name derives from its negative factor thought at the beginning but presently it is remarked as the protein
Keywords
HIV-1 gp120; HIV1 gp120; Envelope surface glycoprotein gp120; Glycoprotein 120; gp120; gp120 glycoprotein; Human Immunodeficiency Virus 1; SU; Surface protein; Retroviridae; Lentivirus; human immunodeficiency virus

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