Gentamicin rapid test strip (Honey) (DTS1020L)

Regulatory status: For research use only, not for use in diagnostic procedures.

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Size
96T
Sample
Honey
Intended Use
Chloramphenicol rapid test strip is developed for rapid test of chloramphenicol contamination in urine.
Storage
The kit can be stored at room temperature (2-30°C). The test kit is stable through the expiration date marked on the foil pouch. DO NOT FREEZE. Do not store the test kit in direct sunlight.
Sensitivity
The sensitivity of gentamicin in honey is 1 ppb.
General Description
Gentamycin is an aminoglycoside antibiotic used to treat infections caused by many different types of bacteria. Gentamycin is usually administered by intravenous infusion or intramuscular injection.

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References


Calcium dobesilate prevents cisplatin-induced nephrotoxicity by modulating oxidative and histopathological changes in mice

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Authors: Bazmandegan, Gholamreza; Fatemi, Iman; Kaeidi, Ayat; Khademalhosseini, Morteza; Fathinejad, Ali; Amirteimoury, Morteza

Cisplatin is one of the synthetic cancer medicines with nephrotoxicity being one of its major side effects. Past research shows that calcium dobesilate (CaD), as a vascular protective agent in diabetic retinopathy, has antioxidant properties. Thus, this study aims to evaluate the protective effects of CaD in cisplatin-induced nephrotoxicity in mice. A many as 28 mice, in the present experimental research, were randomly distributed into four groups, including control, cisplatin (the intraperitoneal administration of 20 mg/kg cisplatin only on the first day of the experiment), cisplatin + CaD 50 (cisplatin with the oral administration of 50 mg/kg CaD), and cisplatin + CaD 100 (cisplatin with the oral administration of 100 mg/kg CaD). The treated groups received CaD by oral gavage for 4 constitutive days. On the fifth day, the mice were sacrificed, and some biochemical (serum levels of Cr and BUN, renal tissue levels of MDA, and renal activities of SOD and GPx) and pathological parameters were evaluated. Based on the results, there was a significant decrease in the renal SOD and GPx activities; in contrast, there was a significant increase in the BUN, Cr, and renal MDA levels following administering cisplatin. However, the CaD treatment (100 mg/kg) significantly attenuated these alterations. In addition, the kidney's histological examination of kidneys confirmed the nephroprotective effects of CaD. The findings proved the protective impact of CaD on cisplatin-induced nephrotoxicity by an improvement in the oxidative stress factors.

Molecular characterization of clinical and environmentalVibrio parahaemolyticusisolates in Huzhou, China

PLOS ONE

Authors: Yan, Wei; Ji, Lei; Xu, Deshun; Chen, Liping; Wu, Xiaofang

Vibrio parahaemolyticusis responsible for seafood-borne gastroenteritis worldwide. Isolates ofV.parahaemolyticusfrom clinical samples (n = 54) and environmental samples (n = 38) in Huzhou were analyzed by serological typing, virulence gene detection, antibiotic resistance testing, and pulsed-field gel electrophoresis (PFGE) for molecular typing. O3:K6 was the main serotype and tlh+tdh+trh- was the most frequently detected virulence genotype in clinical strains. O2:Kut was the main serotype and tlh+tdh-trh- was the most frequently detected virulence genotype in environmental strains. Antibiotic resistance testing indicated that the isolates were highly resistant to ampicillin (90.76%), followed by gentamicin and tetracycline. Following the restriction enzymeNotI digestion, the 91 strains yielded 81 PFGE patterns, and 16 clones had similarity values of > 85.00%, indicating a high level of diversity. Finally, there may be cross-contamination between freshwater and seawater products, so it is necessary to strengthen supervision of food processing.

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