The general structure of quinolones consists of a 1-substituted1,4-dihydro-4-oxopyridine-3-carboxylic moiety, combined with an aromatic or heteroaromatic ring. Nearly all quinolone antibiotics in modern use are fluoroquinolones, which contain a fluorine atom in their chemical structure and are effective against both Gram-negative and Gram-positive bacteria. One example is ciprofloxacin(Cipro), one of the most widely used antibiotics worldwide.
In the veterinary field, quinolones are used for the prophylaxis and treatment of veterinary diseases in most types of farm animals, and in aquaculture, especially in chicken, swine and fish/shrimp farming. The use of quinolones in food producing animals has generated a considerable interest. Quinolones may be directly toxic or be a source of resistant human pathogens, representing a possible risk to human health.
Key quinolone antibiotics analytes in our portfolio:
+ Nalidixic acid