Chloramphenicol

Creative Diagnostics - Food & Feed Analysis

Chloramphenicol

Chloramphenicol antibiotic residues in food of animal origin represent a potential health risk to the consumer. CD offers a portfolio of antibodies, conjugates and test kits for the analysis of chloramphenicol antibiotics.

Chloramphenicol (CAP)

Chloramphenicol (CAP) is a broad spectrum antibiotic obtained originally from the bacterium Streptomyces venezuelae. It is frequently used as a human antibiotic and also as a veterinary drug for its excellent antibacterial and pharmacokinetic properties. The main potential human toxicity is depression of red blood cell production in bone marrow leading to aplastic anemia. Because of the unpredictable effects of dose on different patient populations, the use of CAP in animal-derived foods and animal feed products, including honey from honeybees, has been strictly regulated.

Thiamphenicol (TAP)

Thiamphenicol (TAP) is the methyl-sulfonylanalogue of chloramphenicol and has a similar spectrum of activity, but it is generally 1–2 times less active. Unlike chloramphenicol, thiamphenicol does not cause aplastic anemia in humans.

Florfenicol (FF)

Florfenicol (FF) is a structural analog of thiamphenicol which has greater in vitro activity against pathogenic bacteria than chloramphenicol and thiamphenicol. It is also active against some bacteria that are resistant to chloramphenicol, especially enteric bacteria.

The European Union (EU) has defined a maximum residue limit (MRL) for CAP in food of animal origin at a level of 0.3 µg/kg, while China has an MRL level of 0.5 µg/kg. Thiamphenicol (TAP) and florfenicol (FF) are the analogue compounds of CAP. They can be used as a replacement veterinary antibiotic for CAP in many countries. The maximum residue limits have been set for TAP (50 ng/g) and FF (100 ng/g) in food to date. The CDIATM Chloramphenicol Rapid Test Kits is validated for a wide variety of matrices (milk, honey, meat, fish, shrimp, eggs, feed, plasma and serum)

Key chloramphenicol antibiotics analytes in our portfolio:

+ Chloramphenicol
+ Thiamphenicol
+ Florfenicol

Chloramphenicol (CAP)

Cat. No Product Name Product Type pdf Inquiry Add to basket
DMABT-Z59426 Anti-Chloramphenicol monoclonal antibody, clone D894O Antibody Inquiry
DAG2974 Chloramphenicol [BSA] Conjugate Inquiry
DAG4436 Chloramphenicol [OVA] Conjugate Inquiry
DAG2974K Chloramphenicol [KLH] Conjugate Inquiry
DEIA018 Chloramphenicol, CAP ELISA Kit ELISA Kit Inquiry
DEIA6881 Chloramphenicol ELISA Kit ELISA Kit Inquiry
DTS027 Chloramphenicol Residue Rapid Test Strip (Egg) Rapid Test Kit Inquiry

Florfenicol (FF)

Cat. No Product Name Product Type pdf Inquiry Add to basket
HMABPY042 RHA™ anti-Florfenicol monoclonal antibody, clone ff Antibody Inquiry
DAGP-039H Florfenicol [HRP] Conjugate Inquiry
DAGA-039B Florfenicol [BSA] Conjugate Inquiry
DAGA-042K Florfenicol [KLH] Conjugate Inquiry
DAGA-192B Florfenicol Amine [BSA] Conjugate Inquiry
DAGA-192H Florfenicol Amine [HRP] Conjugate Inquiry
DAGA-192K Florfenicol Amine [KLH] Conjugate Inquiry
DEIA039 Florfenicol and Thiamphenicol ELISA KIT ELISA Kit Inquiry
DISNJ22 Florfenicol Standard solution Standard Inquiry

Thiamphenicol (TAP)

Cat. No Product Name Product Type pdf Inquiry Add to basket
DPATB-H83234 Anti-Thiamphenicol polyclonal antibody Antibody Inquiry
HMABPY041 RHA™ anti-Thiamphenicol drug residue monoclonal antibody, clone tap Antibody Inquiry
DAG1316 Thiamphenicol [HRP] Conjugate Inquiry
DAGA-038B Thiamphenicol Drug [BSA] Conjugate Inquiry
DAGA-031K Thiamphenicol Drug Residue [KLH] Conjugate Inquiry
DISNJ45 Thiamphenicol Standard solution Standard Inquiry
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