Antibiotics

Creative Diagnostics - Food & Feed Analysis

Antibiotics

Antibiotic residues in food of animal origin such as milk, eggs or meat represent a potential health risk to the consumer. CD offers a portfolio of antibodies, antigens and test kits for the analysis of many different antibiotics.

Antibiotics, also called antibacterials, are naturally formed metabolites derived from fungi or bacteria. With advances in medicinal chemistry, most modern antibiotics are semisynthetic modifications of various natural compounds. Antibiotics are able to kill bacteria or keep them from reproducing. In human and veterinary medicine, antibiotics are therefore used in the treatment and prevention of bacterial infections.

Health risks of antibiotic residues in food

Use of Antibiotic that might result in deposition of residues in meat, milk and eggs must not be permitted in food intended for human consumption. If use of antibiotics is necessary as in prevention and treatment of animal diseases, a withholding period must be observed until the residues are negligible or no longer detected. Concern over antibiotic residues in food of animal origin occurs in two times; one which produces potential threat to direct toxicity in human, second is whether the low levels of antibiotic exposure would result in alteration of microflora, cause disease and the possible development of resistant strains which cause failure of antibiotic therapy in clinical situations.

Methods for antibiotic drug residue analysis

The use of screening tests for the detection of antibiotic residues in food is very important. This includes a large variety of detection methods, ranging from physico-chemical analysis (e.g. LC/MS) or immunological detection (e.g. ELISA) to microbiological methods (e.g. growth inhibition tests) and biosensors. Their main advantages are short analysis time, high sensitivity and selectivity for immunoassays, simplicity and low cost for microbiological tests, and automation and the possibility of in situ analysis for biosensors.

More information on specific antibiotics:

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