Inquiry Basket
Loading ......
The renin ELISA kit is a powerful and robust tool designed for the quantitative detection of Renin in human serum, plasma, and cell culture supernatants. Utilizing a sensitive sandwich enzyme-linked immunosorbent assay (ELISA) format, this kit provides researchers with a reliable method to obtain precise data for studying the critical role of the renin-angiotensin system (RAS) in hypertension, cardiovascular diseases, and renal function. Its optimized protocol and ready-to-use components make it an essential asset for any bioanalytical laboratory seeking accuracy and efficiency.
Figure 1. Renin inhibitors.
Renin, a key aspartic protease in the RAAS, initiates the cascade leading to the production of angiotensin II—a potent vasoconstrictor that regulates blood pressure, fluid-electrolyte balance, and tissue remodeling. Abnormal renin expression or activity is closely linked to pathological conditions: elevated renin levels are associated with primary hypertension, renovascular disease, and heart failure, while reduced levels may indicate adrenal insufficiency or congenital hyporeninemia.
Traditional methods for renin detection (e.g., radioimmunoassays, Western blotting) often suffer from limitations such as radioactive hazards, low sensitivity, long turnaround times, or poor specificity for human renin. The Comprehensive Human Renin ELISA Kit overcomes these challenges by using a sandwich ELISA format—pairing highly specific monoclonal antibodies against human renin's conserved epitopes—to ensure selective binding, minimize cross-reactivity with other RAAS components (e.g., angiotensinogen, ACE), and enable precise quantification even in complex biological matrices. This kit is thus an essential tool for researchers investigating RAAS physiology, disease mechanisms, and the efficacy of renin-inhibiting therapeutics (e.g., aliskiren).
Sample Compatibility
Sensitivity Range
Main Uses
Our Human Renin ELISA Kit is meticulously developed and rigorously validated to ensure superior performance.
Core Specifications
Key Features of the Product
Performance Validation
Intended Use
| Parameter | Details |
| Product name | Human Renin ELISA Kit |
| Sample | serum, plasma |
| Intended Use | The product is an enzyme immunoassay for measurement of active Renin in human serum and plasma. |
| Storage | Store all contents at 2-8°C. For more detailed information, please download the following document on our website. |
Ultra-High Sensitivity
The kit uses two highly affinity-purified monoclonal antibodies: the capture antibody binds to renin's N-terminal domain, while the detection antibody targets its catalytic domain—ensuring dual specificity for human renin.
Rigorous Quality Control
Every batch of the kit undergoes strict quality testing: standards are calibrated against international reference materials (e.g., WHO human renin standards), and each microplate is validated for uniformity
treamlined Workflow for Efficient Bioanalysis
Designed for user convenience, the kit requires no complex sample pre-treatment (e.g., protein precipitation) and uses a standardized protocol with clear step-by-step instructions.
The human renin ELISA kit is a reliable, high-performance tool for quantitative human renin bioanalysis. By combining ultra-sensitivity, species-specificity, and operational efficiency, it addresses the core needs of researchers in cardiovascular biology, nephrology, and pharmaceutical development. Whether investigating RAAS-related disease mechanisms, evaluating renin-inhibitor therapeutics, or monitoring clinical samples, this kit delivers accurate, reproducible results that support robust scientific conclusions. Its strict quality control and user-friendly design further make it a valuable asset for both basic research and translational bioanalysis.
A1: The kit should be stored at 2-8°C upon receipt. Under these conditions, all components are stable until the expiration date printed on the box. Do not freeze the reagents.
A2: No. This kit is specifically validated for the detection of human Renin due to the high specificity of the antibodies used. Cross-reactivity with Renin from other species has not been tested and is not guaranteed.
A3: Yes, the microplate strips are pre-coated with a capture antibody specific for human Renin. They are ready to use—just equilibrate to room temperature before adding samples and reagents.
A4: Absolutely. Creative Diagnostics provides comprehensive technical support for all our products. Please contact our technical support team with any questions regarding assay protocol, troubleshooting, or data interpretation.
Loading ......
