Synthetic Human COL11A2 blocking peptide for Apuri, BL, ELISA
Blocking/Immunizing peptide for anti-collagen type XI alpha 2 antibody
collagen type XI alpha 2
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Shipped at ambient temperature, store at -20°C.
This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.
extracellular matrix structural constituent; extracellular matrix structural constituent conferring tensile strength; protein binding, bridging; structural molecule activity;
COL11A2; collagen, type XI, alpha 2; DFNA13, DFNB53; collagen alpha-2(XI) chain; HKE5; pro-a2 chain of collagen type XI; PARP; STL3; FBCG2; DFNA13; DFNB53;