Human COL11A2 blocking peptide (CDBP0847)

Synthetic Human COL11A2 blocking peptide for Apuri, BL, ELISA Datasheet

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Product Overview
Blocking/Immunizing peptide for anti-collagen type XI alpha 2 antibody
Target
collagen type XI alpha 2
Nature
Synthetic
Species Reactivity
Human
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Size
100 μg
Storage
Shipped at ambient temperature, store at -20°C.
UniProt ID
Antigen Description
This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.
Function
extracellular matrix structural constituent; extracellular matrix structural constituent conferring tensile strength; protein binding, bridging; structural molecule activity;
Synonyms
COL11A2; collagen, type XI, alpha 2; DFNA13, DFNB53; collagen alpha-2(XI) chain; HKE5; pro-a2 chain of collagen type XI; PARP; STL3; FBCG2; DFNA13; DFNB53;

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