Product Overview
The UL44 gene for the CMV pp52 antigen has been expressed as a recombinant antigen fused to a his-tag in its N-terminus and in vivo biotinylated
Tag/Conjugate
His, Biotin
Alternative Names
CMV pp52; pp52; HCMV pp52;
Purity
> 95% , as determined by SDS-PAGE
Concentration
Batch dependent - please inquire should you have specific requirements
Buffer
20 mM phosphate buffer pH 6.0 and 0.15 M NaCl
Storage
Store at -20°C to -80°C. Avoid multiple freeze/thaw cycles.
Introduction
Cytomegalovirus is a viral genus of the viral group known as Herpesviridae or herpesviruses. It is typically abbreviated as CMV: The species that infects humans is commonly known as human CMV (HCMV) or human herpesvirus-5 (HHV-5), and is the most studied of all cytomegaloviruses. All herpesviruses share a characteristic ability to remain latent within the body over long periods. Although they may be found throughout the body, CMV infections are frequently associated with the salivary glands in humans and other mammals. Other CMV viruses are found in several mammal species, but species isolated from animals differ from HCMV in terms of genomic structure, and have not been reported to cause human disease.
Antigen Description
pp52 (UL44) is the DNA polymerase processivity subunit of CMV. It is a phosphorylated protein, with a high presence in the virus and DNA binding capacity. pp52 corresponds to an immediate early antigen
Keywords
Cytomegalovirus; CMV pp52; HCMV pp52
Citations
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