urine, serum, plasma and other biological samples.
Intended Use
Enzyme Immunoassay for the quantitative determination of Citrulline in urine, serum, plasma and various biological samples.
Storage
Store the unopened reagents at 2 - 8 C until expiration date. Do not use components beyond the expiry date indicated on the kit labels. Once opened the reagents are stable for 1 month when stored at 2 – 8 °C. Once the resealable pouch has been opened, care should be taken to close it tightly with desiccant again.
Precision
Detection Range
0.23 – 60 μg/ml
Sensitivity
0.23 μg/ml
General Description
Citrulline is a non-essential amino acid. In hepatocytes, L-citrulline is synthesized in the urea cycle by the addition of carbon dioxide and ammonia to ornithine. L-citrulline is converted into L-arginine by the enzymes argininosuccinate synthetase and argininosuccinate lyase in the presence of L-aspartate and ATP. Subsequently, L-arginine is converted to nitric oxide by nitric oxide synthase and L-citrulline is regenerated as a by-product.
Citations
Publication ()
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