Alternative Names
Citreoviridin; CIT; 25425-12-1; 2,5-anhydro-1,6-dideoxy-2-C-[(8-(4-methoxy-5-methyl-2-oxo-2H-pyran-6-yl)-2-methyl-1E,3E,5E,7E-octatetraen-1-yl]-4-C-methyl-D-iditol
Concentration
Batch dependent - please inquire should you have specific requirements.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Introduction
Citreoviridin is a mycotoxin isolated from several Penicillium species that has been shown to inhibit the mitochondrial ATP synthetase system. It inhibits soluble ATPase (KD = 4.1 μM), ADP stimulated respiration in isolated rat liver mitochondria (KD = 0.15 μM), and ATP-driven reduction of NAD+ by succinate (KD = 2 μM). Citreoviridin has been used to target ectopic ATPase activity in cancer cells in order to modulate the metabolic activity associated with tumorigenesis.
Keywords
Citreoviridin;CIT;25425-12-1;2,5-anhydro-1,6-dideoxy-2-C-[(8-(4-methoxy-5-methyl-2-oxo-2Hpyran-6-yl)-2-methyl-1E,3E,5E,7E-octatetraen-1-yl]-4-C-methyl-D-iditol
Citations
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