This ELISA kit is for quantification of CD200 in Canine samples. This is a shorter ELISA assay that reduces time to 50% compared to the conventional method, and the entire assay only takes 3 hours.
Storage
Store the kit at 4°C. The kit can be used in 6 months.
Precision
Intra-Assay %CV: 6; Inter-Assay %CV: 9
Detection Range
125-8,000 pg/ml
Sensitivity
25 pg/ml
General Description
Cluster of Differentiation 200 (CD200) also known as OX-2 membrane glycoprotein and is encoded by the CD200 gene. [1] CD200 is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. CD200 interacts with its receptor CD200R to transmit signals and aberrant expression of CD200/CD200R might play a role in psoriasis vulgaris pathophysiology and disease severity. [2] CD200 is overexpressed in neuroblastoma and regulates tumor immune microenvironment. [3] CD200 down regulates macrophage lineage and basophil function. [4] [5]
Citations
Publication ()
Have you cited DEIASL537 in a publication? Let us know and earn a reward for your research.
Creative Diagnostics products are for RESEARCH USE ONLY, please make sure your review is research based.
Required fields are marked with *
Terms and conditions:
We will select high-quality review customers and offer a $30 coupon for your next purchase.
All product reviews must be submitted in the English language.
Creative Diagnostics will not share any personal information of applicants, and all information will be treated with strict confidentiality and will not be sold or disclosed to a third party.
COA
Publication 
Loading ......
