Product Overview
Human Autotaxin (a.a 49-863) protein was expressed in HEK293 cells and fused to 10xHis at the C-terminus
Alternative Names
Autotaxin; NPP2; ENPP2; ATX
Purity
> 95% , as determined by SDS-PAGE
Concentration
Batch dependent - please inquire should you have specific requirements.
Buffer
PBS with 20% glycerol
Storage
Store at -20°C to -80°C. Avoid multiple freeze/thaw cycles.
Introduction
Autotaxin, also known as ectonucleotide pyrophosphatase/phosphodiesterase 2 (NPP2 or ENPP2), is a secreted enzyme important for generating the lipid signaling molecule lysophosphatidic acid (LPA). Autotaxin has lysophospholipase D activity that converts lysophosphatidylcholine into LPA. Autotaxin was originally identified as a tumor cell-motility-stimulating factor; later it was shown to be LPA (which signals through lysophospholipid receptors), the lipid product of the reaction catalyzed by autotaxin, which is responsible for its effects on cell-proliferation.
Keywords
Autotaxin; E-NPP 2; Lysophospholipase D
Citations
Publication ()
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COA
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