Anti-TNFRSF1A Polyclonal Antibody (CABT-L2075) Knockout Validated

Rabbit Anti-Human TNFRSF1A (Cys248~Met428) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment corresponding to human TNFRSF1A (Cys248~Met428)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-5 ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type Hela cell lysate. Lane 2: TNFRSF1A knockout Hela cell lysate. Predicted MW: 50, 38, 25kDa, Observed MW: 23kDa
Figure. Western Blot. Sample. Lane1: Human Hela Cells; Lane2: Human Jurkat Cells.

Target


Alternative Names
CD120A; P55; TBP1; FPF; TNF-R; TNF-R-I
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adipocytokine signaling pathway; Alzheimers disease; Alzheimers Disease; Amyotrophic lateral sclerosis (ALS); Apoptosis; Apoptosis Modulation and Signaling; Apoptosis Modulation by HSP70; Canonical NF-kappaB pathway;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Cigni, A; Ledda, F; et al. A complex case of renal amyloidosis with a rare co-occurrence of 2 mutations in separate hereditary periodic fever syndrome-related genes. JOURNAL OF NEPHROLOGY 19:543-549(2006).
Li, W; Li, H; et al. Tumor Necrosis Factor Stimulates Matrix Metalloproteinase 9 Secretion from Cultured Human Chorionic Trophoblast Cells Through TNF Receptor 1 Signaling to IKBKB-NFKB and MAPK1/3 Pathway. BIOLOGY OF REPRODUCTION 83:481-487(2010).

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