Anti-SPRY2 Polyclonal Antibody (CABT-L2253) Knockout Validated

Rabbit Anti-Human SPRY2 (Ser116~Thr305) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment corresponding to human SPRY2 (Ser116~Thr305)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.2-2 ug/ml; 1:250-2500
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type A375 cell lysate. Lane 2: SPRY2 knockout A375 cell lysate. Predicted MW: 35kd, Observed MW: 35kd
Western Blot. Sample. Human A375 cell lysate.
Western Blot. Sample. Human Lung lysate.

Target


Alternative Names
SPRY2
Entrez Gene ID
UniProt ID

Product Background


Pathway
Disease; EGFR downregulation; EGFR1 Signaling Pathway; FGF signaling pathway; Internalization of ErbB1; Jak-STAT signaling pathway; MicroRNAs in cancer; Negative regulation of FGFR signaling;

Citations


Have you cited CABT-L2253 in a publication? Let us know and earn a reward for your research.

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

Customer Reviews


Write a review, share your experiences with others and get rewarded !
Product Name Cat. No. Applications Host Species Datasheet Price Add to Basket

References


Peralvarez-Marin, A; Tae, HS; et al. 3D Mapping of the SPRY2 Domain of RyR1 by Antibody Labeling and Single-Particle cryo-EM. BIOPHYSICAL JOURNAL 100:188-188(2011).
Taketomi, T; Yoshiga, D; et al. Loss of mammalian Sprouty2 leads to enteric neuronal hyperplasia and esophageal achalasia. NATURE NEUROSCIENCE 8:855-857(2005).

Online Inquiry

Name:
Phone: *
E-mail Address: *
Service & Products Interested: *
Project Description:
Verification Code: * Please input "diagnostics" as verification code.

Online Inquiry

  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket