Anti-RORa Polyclonal Antibody (CABT-L2157) Knockout Validated

Rabbit Anti-Human RORa (Gln164~Met401) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Mouse
Immunogen
Recombinant fragment corresponding to human RORA (Gln164~Met401)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 1-5 ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type PC3 cell lysate. Lane 2: RORa knockout PC3 cell lysate. Predicted MW: 63kd, Observed MW: 54kd
Figure. Western Blot. Sample. Lane1: Human PC-3 Cells; Lane2: Human Liver Tissue; Lane3: Mouse Kidney Tissue.

Target


Alternative Names
ROR1; ROR2; NR1F1; ROR3; RZRA; Nuclear receptor subfamily 1 group F member 1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adipogenesis; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Circadian Clock; Circadian rhythm; Fatty acid, triacylglycerol, and ketone body metabolism; Gene Expression; Generic Transcription Pathway; Inflammatory bowel disease (IBD);

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References


Ino, H; et al. Immunohistochemical characterization of the orphan nuclear receptor ROR alpha in the mouse nervous system. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 52:311-323(2004).
Baumjohann, D; Kageyama, R; et al. The microRNA cluster miR-17 similar to 92 promotes T-FH cell differentiation and represses subset-inappropriate gene expression. NATURE IMMUNOLOGY 14:840-+(2013).

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