Anti-NNMT Polyclonal Antibody (CABT-L2230) Knockout Validated

Rabbit Anti-Human NNMT (Met1~Arg258) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment corresponding to human NNMT (Met1~Arg258)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-2 ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type A549 cell lysate. Lane 2: NNMT knockout A549 cell lysate. Predicted MW: 30kd, Observed MW: 30kd
Figure. Western Blot. Sample. Lane1: Human Hela Cells; Lane2: Human A549 Cells; Lane3: Human U2OS Cells.
Western Blot. Sample. Human A549 cell lysate.
Western Blot. Sample. Human U2OS cell lysate.

Target


Alternative Names
NNMT
Entrez Gene ID
UniProt ID

Product Background


Pathway
Biological oxidations; Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD); Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD); Defective GGT1 causes Glutathionuria (GLUTH); Defective GSS causes Glutathione synthetase deficiency (GSS deficiency); Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD); Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD); Defective SLC35D1 causes

Citations


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References


Katayama, K; Sasaki, T; et al. Insertional mutation in the Golgb1 gene is associated with osteochondrodysplasia and systemic edema in the OCD rat. BONE 49:1027-1036(2011).

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