Anti-CCT2 Polyclonal Antibody (CABT-L2258) Knockout Validated

Rabbit Anti-Human CCT2 (Met1~Cys488) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Mouse
Immunogen
Recombinant fragment corresponding to human CCT2 (Met1~Cys488)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-2 ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type Hela cell lysate. Lane 2: CCT2 knockout Hela cell lysate. Predicted MW: 57, 53kd, Observed MW: 55kd
Figure. Western Blot. Sample. Lane1: Human Hela Cells; Lane2: Mouse Testis Tissue.

Target


Alternative Names
CCT-beta; CCTB; TCP-1-beta; T-Complex Protein 1 Subunit Beta
Entrez Gene ID
UniProt ID

Product Background


Pathway
Assembly of the primary cilium; Association of TriC/CCT with target proteins during biosynthesis; BBSome-mediated cargo-targeting to cilium; Cargo trafficking to the periciliary membrane; Chaperonin-mediated protein folding; Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding; Folding of actin by CCT/TriC; Formation of tubulin folding intermediates by CCT/TriC;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Seiden-Long, IM; Brown, KR; et al. Transcriptional targets of hepatocyte growth factor signaling and Ki-ras oncogene activation in colorectal cancer. ONCOGENE 25:91-102(2006).
Zhu, H; Luo, LY; et al. Treating Alzheimer's disease with Yizhijiannao granules by regulating expression of multiple proteins in temporal lobe. NEURAL REGENERATION RESEARCH 9:1283-1287(2014).

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