Product Overview
Alpha-Tocopherol, BSA-conjugated
Specificity
Alpha-Tocopherol (vitamin E) conjugated with Succinic acid (Su) and bovine serum albumin (BSA).
Storage
2-8°C short term, -20°C long term
Reconstitution
Reconstitute with deionized water (250 μg)
Introduction
Alpha-Tocopherol is the orally bioavailable alpha form of the naturally-occurring fat-soluble vitamin E, with potent antioxidant and cytoprotective activities. Upon administration, alpha-tocopherol neutralizes free radicals, thereby protecting tissues and organs from oxidative damage. Alpha-tocopherol gets incorporated into biological membranes, prevents protein oxidation and inhibits lipid peroxidation, thereby maintaining cell membrane integrity and protecting the cell against damage. In addition, alpha-tocopherol inhibits the activity of protein kinase C (PKC) and PKC-mediated pathways. Alpha-tocopherol also modulates the expression of various genes, plays a key role in neurological function, inhibits platelet aggregation and enhances vasodilation. Compared with other forms of tocopherol, alpha-tocopherol is the most biologically active form and is the form that is preferentially absorbed and retained in the body.
Keywords
alpha-Tocopherol; VITAMIN E; D-alpha-Tocopherol; 5,7,8-Trimethyltocol
Citations
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