Aflatoxin M1 rapid test strip

Sample

Goat milk,Goat milk powder

Intended Use

This kit is used for rapid qualitative analysis of Aflatoxin M1 in Goat milk.

Storage

Store the unopened product at 2-8°C. Do not use past expiration date.
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Detection Limit

0.075-0.1ppb

General Description

The aflatoxins are agroup of closely related mycotoxins that are widely distributed in nature.The most important of the group is aflatoxin B1 (AFB1), which has a range of biological activities, including acute toxicity, teratogenicity, mutagenicityand carcinogenicity. In order for AFB1 to exert its effects, it must beconverted to its reactive epoxide by the action of the mixed functionmono-oxygenase enzyme systems (cytochrome P450-dependent) in the tissues (inparticular, the liver) of the affected animal. This epoxide is highlyreactive and can form derivatives with several cellular macromolecules,including DNA, RNA and protein. Cytochrome P450 enzymes may additionallycatalyse the hydroxylation (to AFQ1 and AFM1) and demethylation (to AFP1) ofthe parent AFB1 molecule, resulting in products less toxic than AFB1.Conjugation of AFB1 to glutathione (mediated by glutathione S-transferase)and its subsequent excretion is regarded as an important detoxificationpathway in animals.