The Abatacept ELISA has been especially developed for the quantitative analysis of free abatacept in serum and plasma samples.
Storage
The kit is shipped at ambient temperature (10-30°C) and should be stored at 2-8°C for long term storage. Keep away from heat or direct sunlight. The strips of microtiter plate are stable up to the expiry date of the kit in the broken, but tightly closed bag when stored at 2-8°C.
Precision
Intra-assay and inter-assay CVs < 30%
Sensitivity
The lowest detectable level (Lowest detection limit, LOD) that can be distinguished from the zero standard is 3 ng/mL. Functional sensitivity (Limit of quantification-LOQ): 3 ng/mL
General Description
Abatacept (CTLA4Ig) is a fusion protein of the extracellular domain of the human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) linked to a modified Fc of human immunoglobulin 1 (IgG1). Abatacept inhibits the activation of T lymphocytes that play an important role in the early stages of pathogenesis of RA.
Citations
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