Product Overview
Titer: 1x10E13 VG/ml-Promotor: CMV-No insert gene
Tag/Conjugate
Unconjugated
Alternative Names
AAV; AAV2; AAV 2; Adeno-associated virus; Adeno-associated virus 2; Adeno-associated virus type 2
Buffer
PBS with 5% glycerol
Introduction
Adeno-Associated Virus (AAV) is a nonpathogenic virus species that belongs to the Parvoviridae family. AAV is classified as small (25nm) and contains a single-stranded nonenveloped DNA genome. Infection with AAV occurs only with the help of other viruses, either herpesvirus or adenovirus (hence adeno-associated virus), causing only a very mild immune response in humans. There are twelve serotypes of human AAV but the number of nonhuman AAVs exceeds 100. AAV2 is the only mammalian DNA virus that is known to integrate in a specific site of the genome.
Keywords
AAV; AAV2; AAV 2; Adeno-associated virus; Adeno-associated virus 2; Adeno-associated virus type 2
Citations
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Rodriguez, E; Keiser, M; et al. AAV-CRISPR: A New Therapeutic Approach To Nucleotide Repeat Diseases. MOLECULAR THERAPY 22:S94-S94(2014).
Bello, A; Chand, A; et al. Novel Adeno-associated Viruses Derived From Pig Tissues Transduce Most Major Organs in Mice. SCIENTIFIC REPORTS 4:-(2014).
COA
Certificate of Analysis
