Human ZEB2 blocking peptide (CDBP3234)

Synthetic Human ZEB2 blocking peptide for BL

Product Overview
Blocking peptide for anti-ZEB2 antibody
Target
ZEB2
Nature
Synthetic
Species Reactivity
Human
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not suitable for human or animal consumption.
Procedure
None
Format
Liquid
Concentration
200 μg/ml
Size
50 μg
Buffer
PBS containing 0.02% sodium azide
Preservative
0.02% Sodium Azide
Storage
Store at -20℃, stable for one year.
UniProt ID
Antigen Description
The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010]
Function
SMAD binding; metal ion binding; phosphatase regulator activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; zinc ion binding;
Synonyms
ZEB2; zinc finger E-box binding homeobox 2; ZFHX1B, zinc finger homeobox 1b; zinc finger E-box-binding homeobox 2; KIAA0569; SIP 1; SIP1; SMAD interacting protein 1; zinc finger homeobox 1b; Smad-interacting protein 1; SIP-1; ZFHX1B; HSPC082; SMADIP1; FLJ42816;

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References


Differentiation of Trophoblast Cell Lines to an Extravillous Phenotype is Driven by Overexpression of the ZEB2 Transcription Factor, Producing Substantial Increases in Invasiveness.

REPRODUCTIVE SCIENCES

Authors: DaSilva-Arnold, Sonia; Kuo, Che-Ying; Kim, Peter C. W.; Fisher, John P.; Zamudio, Stacy; Al-Khan, Abdulla; Illsley, Nicholas P.

A p53/miR-30a/ZEB2 axis controls basal-like/triple-negative breast cancer aggressiveness

CANCER RESEARCH

Authors: Damiano, Valentina; di Gennaro, Alessandra; Brisotto, Giulia; Armellin, Michela; Perin, Tiziana; Zucchetto, Antonella; Guardascione, Michela; Spaink, Herman P.; Doglioni, Claudio; Snaar-Jagalska, Ewa; Santarosa, Manuela; Maestro, Roberta

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