The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Function
poly(A) RNA binding; protein transporter activity;
Synonyms
USO1; USO1 vesicle transport factor; TAP; VDP; P115; general vesicular transport factor p115; vesicle docking protein p115; transcytosis associated protein; USO1 vesicle docking protein homolog;
Citations
Publication ()
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