Human Thyroglobulin, natural protein
Native human Thyroglobulin
SDS-PAGE (purity > 95%).
0.7-1.0 μg/ml (depending on the type of ELISA plate and coating buffer). Suitable for labeling of functional groups.
2-8°C short term, -20°C long term
Thyroglobulin (TG) represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. TG is a large globular dimeric glycoprotein with a total molecular weight of 660 kDa, which occupies a key precursor role in the biosynthesis of the thyroid hormones. Approximately 75% of the total protein content of the thyroid follicle consist of TG. TG autoantibodies of IgG type have a prevalence of 80-85% in patients with Hashimoto thyroiditis and also a lower prevalence of 30-80% in patients with Graves' disease.
thyroglobulin; 11764; Ensembl:ENSG00000042832; thyroglobulin; TG; TGN; AITD3