Testosterone-3 [HRP] (DAG1309)

Product Overview
Testosterone-3, HRP conjugate
Target
Testosterone
Nature
Synthetic
Tag/Conjugate
HRP
Application Notes
Matched pair antibody available for Testosterone [HRP]: Testosterone antibody (Catalog # HMABPY021)
Format
Liquid
Concentration
Batch dependent - please inquire should you have specific requirements
Size
1 ml
Buffer
0.05M Tris, pH 7.0
Preservative
0.005% Thimerosal
Storage
Store at 2-8°C, do not freeze
Warnings
PLEASE note that this product is intended for research use only; not for diagnostic or clinical use.
Introduction
Testosterone is a steroid sex hormone found in both men and women. In men, testosterone is produced primarily by the Leydig (interstitial) cells of the testes when stimulated by luteinizing hormone (LH). It functions to stimulate spermatogenesis, promote physical and functional maturation of spermatozoa, maintain accessory organs of the male reproductive tract, support development of secondary sexual characteristics, stimulate growth and metabolism throughout the body and influence brain development by stimulating sexual behaviors and sexual drive. In women, testosterone is produced by the ovaries (25%), adrenals (25%) and via peripheral conversion from androstenedione (50%). Testerone in women functions to maintain libido and general wellbeing. Testosterone exerts a negative feedback mechanism on pituitary release of LH and follicle-stimulating hormone (FSH). Testosterone may be further converted to dihydrotestosterone or estradiol depending on the tissue.
Keywords
Testosterone; Hormones; 17β-Hydroxyandrost-4-en-3-one

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References


Kumar, S; Yadav, RN; et al. Prostatic hyperplasia in acromegaly, a myth or reality: a case-control study. EUROPEAN JOURNAL OF ENDOCRINOLOGY 172:-(2015).
Han, XF; Gu, LJ; et al. Effect of immunization against GnRH on hypothalamic and testicular function in rams. THERIOGENOLOGY 83:642-649(2015).

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