HIV Tat 48-60 5-FAM (DAG4431)
HIV Tat 48-60 5-FAM, synthetic
Datasheet
Product Overview
HIV Tat 48-60 5-FAM
Nature
Synthetic
Tag/Conjugate
Unconjugated
Storage
2-8°C short term, -20°C long term
Introduction
The human immunodeficiency virus (HIV) is a lentivirus (slowly replicating retrovirus) that causes the acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells.
Antigen Description
The transcriptional transactivator (Tat) is a key regulatory protein of HIV. It is expressed early after the virus integrates into the cell, and stimulates the elongation of RNA polymerase II. It binds onto a sequence known as the TAR, or transactivator r
Keywords
p14; Tat; Tat protein; Transactivating regulatory protein; HIV tat
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