Product Overview
Blocking/Immunizing peptide for anti-TUSC3/N33 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene is a candidate tumor suppressor gene. It is located within a homozygously deleted region of a metastatic prostate cancer. The gene is expressed in most nonlymphoid human tissues including prostate, lung, liver, and colon. Expression was also detected in many epithelial tumor cell lines. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Function
contributes_to dolichyl-diphosphooligosaccharide-protein glycotransferase activity; magnesium ion transmembrane transporter activity;
Synonyms
TUSC3; tumor suppressor candidate 3; M33; N33; MRT7; MRT22; OST3A; D8S1992; magnesium uptake/transporter TUSC3; oligosaccharyltransferase 3 homolog A; Putative prostate cancer tumor suppressor;
Citations
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Kim, JY; Park, HS; et al. Functional analysis of expressed sequence tags from the liver and brain of Korean Jindo dogs. BMB REPORTS 44:238-243(2011).
Molinari, F; Foulquier, F; et al. Oligosaccharyltransferase-subunit mutations in nonsyndromic mental retardation. AMERICAN JOURNAL OF HUMAN GENETICS 82:1150-1157(2008).