Human TSLP blocking peptide (CDBP3090)

Synthetic Human TSLP blocking peptide for BL

Product Overview
Blocking peptide for anti-TSLP antibody
Target
TSLP
Nature
Synthetic
Species Reactivity
Human
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not suitable for human or animal consumption.
Procedure
None
Format
Liquid
Concentration
200 μg/ml
Size
50 μg
Buffer
PBS containing 0.02% sodium azide
Preservative
0.02% Sodium Azide
Storage
Store at -20℃, stable for one year.
UniProt ID
Antigen Description
This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Function
cytokine activity;
Synonyms
TSLP; thymic stromal lymphopoietin;

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References


Sano, Y; Masuda, K; et al. Thymic stromal lymphopoietin expression is increased in the horny layer of patients with atopic dermatitis. CLINICAL AND EXPERIMENTAL IMMUNOLOGY 171:330-337(2013).
Han, JY; Dakhama, A; et al. Responsiveness to respiratory syncytial virus in neonates is mediated through thymic stromal lymphopoietin and OX40 ligand. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 130:1175-+(2012).

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