Product Overview
Blocking/Immunizing peptide for anti-TRPV3 (aa610-622) antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene product belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. This gene lies in close proximity to another family member gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Synonyms
TRPV3; cation channel TRPV3;
Citations
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Hu, J; Choo, HJ; et al. Infrared heat treatment reduces food intake and modifies expressions of TRPV3-POMC in the dorsal medulla of obesity prone rats. INTERNATIONAL JOURNAL OF HYPERTHERMIA 27:708-716(2011).
Suh, E; Matic, AI; et al. Optical stimulation in mice lacking the TRPV1 channel. PHOTONS AND NEURONS 7180:-(2009).