Human TRIM5 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-TRIM5/RNF88 antibody

Target

TRIM5 / RNF88

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2009]

Function

ligase activity; metal ion binding; protein binding; protein homodimerization activity; zinc ion binding;

Synonyms

TRIM5; tripartite motif containing 5; tripartite motif-containing protein 5; RNF88; TRIM5alpha; tripartite motif protein TRIM; tripartite motif protein TRIM5; ring finger protein 88; tripartite motif containing 5 transcript variant iota; tripartite motif containing 5 transcript variant kappa;