Product Overview
Blocking/Immunizing peptide for anti-TRIM37 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Function
ligase activity; metal ion binding; protein binding; zinc ion binding;
Synonyms
TRIM37; tripartite motif containing 37; MUL, tripartite motif containing 37; E3 ubiquitin-protein ligase TRIM37; KIAA0898; POB1; RING B box coiled coil protein; TEF3; mulibrey nanism protein; RING-B-box-coiled-coil protein; tripartite motif-containing 37; tripartite motif-containing protein 37; MUL;
Citations
Publication ()
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