Product Overview
Blocking/Immunizing peptide for anti-TRIM23 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. [provided by RefSeq, Jul 2008]
Function
GDP binding; GTP binding; GTPase activity; enzyme activator activity; ligase activity; metal ion binding; nucleotide binding; protein binding; ubiquitin-protein ligase activity; zinc ion binding;
Synonyms
TRIM23; tripartite motif containing 23; ADP ribosylation factor domain protein 1, 64kDa , ARFD1, tripartite motif containing 23; E3 ubiquitin-protein ligase TRIM23; ARD1; RNF46; ARF domain protein 1; RING finger protein 46; GTP-binding protein ARD-1; tripartite motif-containing 23; tripartite motif protein TRIM23; tripartite motif-containing protein 23; ADP-ribosylation factor domain protein 1, 64kDa; ADP-ribosylation factor domain-containing protein 1; ARFD1;
Citations
Publication ()
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