Specificity
Highest expression in heart, skeletal muscle and pancreas. Less abundant in kidney, placenta and brain. Lowest expression in kidney and liver.
Tag/Conjugate
Unconjugated
SequenceSimilarities
Belongs to the splicing factor SR family.Contains 1 RRM (RNA recognition motif) domain.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Antigen Description
This gene encodes a nuclear protein which functions as sequence-specific serine/arginine splicing factor which plays a role in mRNA processing, splicing patterns, and gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Function
mRNA binding; nucleotide binding; poly(A) RNA binding; protein binding;
Synonyms
TRA2B; transformer 2 beta homolog (Drosophila); SFRS10; SRFS10; TRAN2B; TRA2-BETA; Htra2-beta; transformer-2 protein homolog beta; TRA-2 beta; transformer-2 protein homolog B; splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila);
Citations
Publication ()
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COA
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