SPRED2 is a member of the Sprouty (see SPRY1; MIM 602465)/SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (see MAPK1; MIM 176948) (Nonami et al., 2004 [PubMed 15465815]).[supplied by OMIM, Mar 2008]
Function
protein binding; protein kinase binding; protein serine/threonine kinase inhibitor activity; stem cell factor receptor binding
Synonyms
SPRED2; sprouty-related, EVH1 domain containing 2; Spred-2; sprouty-related, EVH1 domain-containing protein 2; sprouty protein with EVH-1 domain 2, related sequence
Citations
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