Product Overview
Spermine, BSA-conjugated
Specificity
Spermine conjugated with glutaraldehyde (G) and bovine serum albumin (BSA).
Purity
Purity is greater than 90.0% as determined by SDS-PAGE
Storage
2-8°C short term, -20°C long term
Introduction
Spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. Formed from spermidine, it is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria. It is found as a polycation at physiological pH. Spermine is associated with nucleic acids and is thought to stabilize helical structure, in particular, in viruses.
Citations
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Shelton, JL; Wang, LF; et al. Human neutrophil-pulmonary microvascular endothelial cell interactions in vitro: Differential effects of nitric oxide vs. peroxynitrite. MICROVASCULAR RESEARCH 76:80-88(2008).
Zhang, W; Ramdas, L; et al. Apoptotic response to 5-fluorouracil treatment is mediated by reduced polyamines, non-autocrine Fas ligand and induced tumor necrosis factor receptor 2. CANCER BIOLOGY & THERAPY 2:572-578(2003).
COA
Certificate of Analysis