Human DIABLO blocking peptide

Product Overview

Smac ( C - term ) peptide ( human )

Target

Smac

Nature

Synthetic

Tag/Conjugate

Unconjugated

Concentration

0.2 mg/ml

Buffer

PBS with 0.1% BSA 0.02% sodium azide pH7.2

Preservative

0.02% Sodium Azide

Storage

Upon Receipt - Keep as concentrated solution. Aliquot and store at -20℃ or below. Avoid freeze-thaw cycles.

Gene ID

56616

UniProt ID

K7X1S0

Antigen Description

This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. (provided by RefSeq, May 2013)

Function

protein binding;

Synonyms

DIABLO; diablo, IAP-binding mitochondrial protein; SMAC; DFNA64; diablo homolog, mitochondrial; direct IAP-binding protein with low pI; second mitochondria-derived activator of caspase;