Tag/Conjugate
Unconjugated
Antigen Description
Members of the SLITRK family, such as SLITRK5, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK5, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]).[supplied by OMIM, Mar 2008]
Synonyms
SLITRK5; SLIT and NTRK-like family, member 5; LRRC11; bA364G4.2; SLIT and NTRK-like protein 5; slit and trk like gene 5; leucine rich repeat containing 11; leucine-rich repeat-containing protein 11
Citations
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Wu, K; Hanna, GL; et al. Glutamate system genes and brain volume alterations in pediatric obsessive-compulsive disorder: A preliminary study. PSYCHIATRY RESEARCH-NEUROIMAGING 211:214-220(2013).
Mah, AK; et al. SLITRK5, a protein that links striatal deficits to OCD-like behaviours in mice. CLINICAL GENETICS 78:350-352(2010).
COA
Certificate of Analysis
