Human SLC10A2 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-SLC10A2/ASBT antibody

Target

SLC10A2 / ASBT

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq, Mar 2010]

Function

bile acid:sodium symporter activity; symporter activity;

Synonyms

SLC10A2; solute carrier family 10, member 2; ileal sodium/bile acid cotransporter; IBAT; ileal Na(+)/bile acid cotransporter; Na(+)-dependent ileal bile acid transporter; ileal sodium-dependent bile acid transporter; apical sodium-dependent bile acid transporter; sodium/taurocholate cotransporting polypeptide, ileal; ASBT; ISBT;